The potential of a novel biosorbent Swietenia mahagoni fruit shell (SMFS) has been investigated for the confiscation of Cr(VI) from aqueous solution. The significant biosorption process parameters like pH, Cr(VI) concentrations and contact time were analyzed. Langmuir, Freundlich and Elovich isotherm models were used to model the adsorption equilibrium data. The Langmuir isotherm model better fitted the equilibrium data and the maximum adsorption capacity has been found as 2.309 mg g-1 .The kinetics studies demonstrated the pseudo first order rate lagergren model and pseudo second order. The biosorption process obeyed the pseudo second-order mode more than the pseudo first-order rate lagergren model. The biosorbent has been characterized through FTIR, SEM and EDAX respectively. The present studies revealed that SMFS could be subjected as an efficient biosorbent for the removal of Cr(VI) from aqueous solution.