4 Nitrophenol (NP) or para nitrophenol (PNP) is one of the emerging pollutants from pesticides industries and it is a major discharge from any phenol consuming industry and also severs as a major discharge from pharmaceutical wastewater. Design and development of photocatalytic treatment of p-nitrophenol particularly to suit recovery and reuse of catalyst will aid in its commercial scale development. P-nitrophenol degradation has been studied in cellulose acetate immobilized TiO2 in a continuous photocatalytic reactor. The prepared catalyst were characterized using SEM, DRS-UV, XRD, FT-IR. The degradation efficiency is studied for varying the pH, catalyst dosage and also the supports. The overall degradation of p-nitrophenol of 89 % was observed for cellulose acetate doped TiO2 (CA/TiO2) than compared to bare TiO2 (74 %). The kinetics was pseudo first order kinetics and mechanism of p-nitrophenol degradation was also discussed.