In this paper, we introduce an innovative, extremely sensitive microwave sensor that is based on Spoof Surface Plasmon Polariton (SSPP) like propagation and has an integrated chamber for liquid samples. By examining the impacts of variations in geometrical parameters on sensor responses, sensor performance is optimized for the ultra-sensitive identification of tiny dielectric constant in liquid specimens. When the sensor is loaded with a different sample, the variation in the resonance frequency is subsequently acquired. The findings show that the sensor has a high sensitivity 1055 MHz/epsilon unit and good linearity R2 = 0.927. The proposed sensor is a strong contender for the identification of minute variations in the dielectric constant of various samples.