In this study, a dimension reduction procedure of defect properties is proposed together with a two dimensional dislocation dynamics framework in order to simulate tensile response of the materials at different levels of external conditions such as radiation. This procedure delivers ordered pairs of strength and line density according to the changes in the geometrical properties of the defects. Plain strain deformation of irradiated oxygen-free high conductivity copper is investigated by using experimental information about the evolution of stacking-fault tetrahedra at the irradiation doses of 0-0.2 dpa. © 2014 Elsevier B.V. All rights reserved.