This paper presents a method for improvement in SNR and resolution of photo acoustic (PA) signal using Golay coded excitation for a non-invasive and continuous glucose monitoring. The simulation results with a Golay code of length 4 has been shown, which gives a coding gain of 9.03 dB in comparison to regular pulse triggering. Furthermore, Golay coded excitation results in better resolution of PA signal as compared to coherent averaging technique, which can help in improving calibration accuracy. © 2014 IEEE.