�Abstract: This paper admits a LNA (low noise amplifier) designed by taking bio-medical applications in to considerations. The amplifier is designed based on two gain stages, supply insensitive gain stage and inverter gain stage. Input-referred noise of the proposed amplifier is 18.02 mVrms and it consumes a power of 0.012 mW. The amplifier produces a gain of 86.5 dB. Bandwidth of the proposed amplifier is 227 Hz with cut-off frequencies as 227 Hz (higher) and 1 mHz (lower). The entire system is built in 45-nm technology with supply voltage of 0.6 V.