A linear approach to fault analysis in Boolean networks

Publications

A linear approach to fault analysis in Boolean networks

Year : 2017

Publisher : Institute of Electrical and Electronics Engineers Inc.

Source Title : Proceedings of the American Control Conference

Document Type :

Abstract

Diagnostics and therapeutic interventions in complex systemic diseases like cancer can be mapped to fault identification and control problem. A complete linear framework has been developed in this manuscript to comprehend different classes of faults and controllability of the output for a class of homeostatic inputs in the Boolean network framework. The problems undertaken in this manuscript are non-trivial. Interesting results have been derived for fault identification and control in the linearised Boolean network model of a proliferating cellular system.