Biomass utilization as an adsorbent for water treatment is an important aspect of environmental protection efforts. It gives a two-pronged advantage of waste valorization and environmental pollution control. In this chapter, the research efforts on water pollutants removal using adsorbents prepared using avocado (Persea americana) biomass was reviewed. Chemical modification by wet impregnation of acids and/or salts is the most utilized techniques for the treatment/activation of avocado-based adsorbents. The avocado adsorbents with higher specific surface area were those that underwent thermochemical processing while the biosorbents had relatively lesser specific surface area. Avocado-based adsorbents were efficient for the removal of dyes, heavy metals, and other water pollutants. Equilibrium isotherm modeling revealed the Langmuir and Sips isotherms as best-fits in most cases while the pseudo-second order model was the best-fit kinetics model in most cases. Though there were no general observations from the thermodynamics analysis, the parameters dependent on the nature of the adsorbent and adsorbate materials. For future work, the review suggested that the lifecycle analysis of adsorbent production and utilization, and cost analysis be performed. It can be surmised that avocado bears great potential for utilization as an adsorbent for water pollution remediation.