In recent times, plastic pollution had an adverse impact on the environment due to a high level of fragmentation. Consequently, as plastic waste gets accumulated in various water bodies, there is a need for sustainable and efficient mitigation techniques. The generation of plastic pollution is due to the unsustainable consumption and disposal of plastic products, which further threatens the environment, economy, as well as human health. This book chapter will discuss the possible solutions to reduce the use of single-use plastics, increase the use of biodegradable plastics, and impose a plastic tax to minimize plastic usage and plastic pollution. Typically, mismanaged waste emerges as one of the major sources of plastic pollution which can be further minimized through enhancements in the life cycle of plastics, especially during production, consumption, and disposal. The book chapter will also discuss the recent practices to manage waste plastics and minimize plastic pollution. Thus, a comprehensive approach is highly required which combines with technology advocacy and policy making to eradicate the issue of plastic pollution.