Li-Fi networks provide high indoor throughput but face challenges due to their reliance on line-of-sight (LoS) and limited coverage. User mobility can degrade throughput as movement beyond a single access point (AP) reduces signal quality, while deploying multiple APs introduces interference and signal fluctuations. This paper uses the random waypoint mobility model to analyze how device orientation impacts signal-to-interference-plus-noise ratio (SINR) and throughput in dynamic indoor environments. Results show that orienting user devices toward a Li-Fi AP enhances SINR in high-interference areas, while a non-oriented state improves throughput in low-interference regions by preserving LoS. The proposed strategy dynamically adjusts device orientation based on real-time SINR and channel conditions, balancing interference reduction and LoS preservation. This adaptive approach optimizes network performance under varying mobility and interference scenarios, improving throughput and reliability in Li-Fi networks.