India’s government spends 1.5 percent of its annual GDP on public healthcare, which is significantly less than that of other countries. Global public health spending, on the other hand, has almost doubled in line with inflation in the last two decades, reaching US $8.5 trillion in 2019, or 9.8% of global GDP. Multinational multi-private sectors provide around 60% of comprehensive medical treatments and 70% of out-patient care, which charge patients astronomically high fees. Because of the rising expense of quality healthcare, increased life expectancy, and the epidemiological shift toward non-communicable diseases, health insurance is becoming an essential commodity for everyone. Insurance data has increased dramatically in the last decade, and carriers now have access to it. The health insurance system explores predictive modeling to boost its business operations and services. Computer algorithms and Machine Learning (ML) is used to study and analyze the past insurance data and predict new output values based on trends in customer behavior, insurance policies, and data-driven business decisions, and support in formulating new schemes. Additionally, ML has found enormous and potential applications in the insurance industry. Thus, this paper develops a real-time insurance cost price prediction system named ML Health Insurance Prediction System (MLHIPS) using ML algorithms which will aid the insurance companies in the market for easy and rapid determination of values of premiums and thereby curb down health expenditure. The proposed model incorporates and demonstrates different models of regression such as Ridge Regression, Lasso Regression, Simple Linear Regression, Multiple Linear Regression and Polynomial Regression to anticipate insurance costs and assess model outcomes. In the proposed model, the Polynomial Regression model has achieved better results with an RMSE value of 5100.53 and R -squared value of 0.80 compared to all the other models.