Direct heating of droplets for chemical and biological reactions on lab-on-chip devices using high frequency AC voltage

Publications

Direct heating of droplets for chemical and biological reactions on lab-on-chip devices using high frequency AC voltage

Year : 2020

Publisher : Chemical and Biological Microsystems Society

Source Title : 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Document Type :

Abstract

We demonstrate a novel concept to heat a drop. Temperature rise occurs when high frequency (10-50 kHz) AC actuation voltage (270 Vrms-460 Vrms) is applied on the dielectric coated coplanar electrodes. The temperature rise (up to 40 °C) inside the drop provides calibrated high temperatures for enabling chemical reactions on Lab-on a-Chip devices. Droplet spreading along the electrode gap happens as this actuation regime also coincides with dielectrophoresis. The proposed technique does not require separate microheaters on the chip as electrodes designed for droplet actuation can be used to achieve localized heating.