Current study explores the understanding of various parameters such as the role of aluminum powder dosage, water-to-binder ratio, and initial curing temperature on the production of lightweight blocks. Three different cementitious systems were used: limestone calcined clay cement (LC3), Portland pozzolana cement, and ordinary Portland cement. The aluminum powder dosage and the water-to-binder ratio clearly influence the hardened properties of blocks, whereas the initial curing temperature does not show much improvement to overall properties. Hardened properties such as dry density, compressive strength, and water absorption of blocks were evaluated. The required aluminum powder dosage varies from system to system, and it depends on the required density. To maintain lower density, OPC system required higher dosage of Al powder, and it showed lower strength compared to other systems. LC3-based lightweight blocks are produced with 3 MPa strength, and it showed good performance compared to other systems.