Large portion of wind turbine blade is sandwich construction made out of glass fiber/epoxy composite face sheet with foam core. The objective of the current study is to evaluate alternate core materials suitable for blade shell sandwich applications for low cost and low weight. Various commercially available core materials are evaluated analytically for panel level buckling performance and aerial weight for relative comparison of core material. Based on structural and cost analysis, Webcore structural core material is selected for blade shell application and experimentally evaluated for its properties, such as density, shear modulus, compression modulus and tensile modulus, to compare with currently used PVC foam core. Buckling tests of sandwich panel are conducted to evaluate core materials performance for wind blade application. Webcore materials proved to be better candidates for wind blade applications as compared to PVC foam core.