Implementation of Diverse Nano-cargos to Disguise and Fight Multidrug Resistance

Publications

Implementation of Diverse Nano-cargos to Disguise and Fight Multidrug Resistance

Implementation of Diverse Nano-cargos to Disguise and Fight Multidrug Resistance

Year : 2022

Publisher : Springer International Publishing

Source Title : Emerging Modalities in Mitigation of Antimicrobial Resistance

Document Type :

Abstract

Advent in nanoscience and nanotechnology has opened new avenues in terms of nanoparticle utilization as novel drug delivery cargos to fight various pathogens. The essential salient features of these nano-cargos along with the surface chemistries that are involved to accommodate drug modalities are described. Emerging aspects of selective targeting mechanisms including pH trigger, systemic responses, overexpression of relevant biomolecules and controlled release are highlighted illustrating suitable examples. Finally, limitations on the use of nano-carriers for drug delivery and various strategies that are implemented to overcome the bio-hurdles are presented.