Abstract
Food is the most basic need for human civilisation to survive. To meet this food requirement edible plants or crops have been domesticated and cultivated by the human race since time immemorial. The continuous population outburst leads to acute food scarcity in two ways, firstly it increases dramatic demand; secondly agricultural lands reduce readily due to massive urbanisation. The yield loss due to various biotic and abiotic stresses makes the situation further detrimental. The sufficient quality food for every individual has been put into question. The scientists are continuously put their effort to overcome the effects of different stress factors, which impart in the plants improved resistance, better growth rate and high yield output. The Genetically Modified Plants are one of the results of these efforts. They are much superior in handling stress conditions but their successful commercialization faces several social restrictions. Thus, various biosafety measures have been undertaken and implemented in order to handle these crops and commercialise the same with proper quality-control. This manuscript provides a brief overview of biotic stress, the need for biotic stressresistant plants, and biotechnological approach to develop stress resistance in crop plants. It also discusses the issues and concerns arise with the use of these biotech crops and the present scenario of biosafety protocols for overcoming the situation.