Guest Solvent-dependence of the Nanomechanical Response in Substituted Dihydropyrimidinone Crystals

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Guest Solvent-dependence of the Nanomechanical Response in Substituted Dihydropyrimidinone Crystals

Guest Solvent-dependence of the Nanomechanical Response in Substituted Dihydropyrimidinone Crystals

Year : 2019

Publisher : John Wiley and Sons LtdSouthern GateChichester, West SussexPO19 8SQvgorayska@wiley.com

Source Title : Chemistry - An Asian Journal

Document Type :

Abstract

The nanomechanical responses of two crystalline phases of a dihydropyrimidine analogue (1) were similar irrespective of the presence (or absence) of the guest solvent. In contrast, the mechanical responses of two differently solvated forms of the second related (2) crystals were significantly different. These contrasting behaviors are rationalized in terms of intermolecular interactions and energy distributions.