Projects
Department of Biological Sciences
Projects
| Title | PI/Co-PI | Funding Type / Agency | Period Support | Duration (In Years) | Status |
|---|---|---|---|---|---|
| Architecture of Rotavirus | Dr C Durga Rao | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Acinetobacter baumannii biofilm disruption at different biofilm lifecycle stages using a molecular disruptor and its mechanism of action | Dr Jayaseelan Murugaiyan | Sponsoring Agency SRM University - AP |
2025- | 1 | On Going |
| Design of RNA-structure-guided antisense oligonucleotide for rescuing UNC13A mis-splicing in amyotrophic lateral sclerosis (ALS) | Dr Kaushik Saha | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Examining sialic acid cleavage, uptake, and its role in molecular mimicry and host attachment by Acinetobacter baumanii to modify therapeutic targets in host-pathogen interactions | Dr Sudeshna Saha, Dr Kaushik Saha | Govt ICMR |
2026-2029 | 4 | Upcoming |
| Genomic Surveillance-based Clinical Bacteriophage therapy against patient-derived multi-drug resistant pathogens | Dr Sutharsan Govindarajan | Sponsoring Agency |
2025- | 1 | On Going |
| Isolation of bacteriophages specific to Acinetobacter baumannii and exploring phage binding to the receptors on multidrug-resistant Gram-negative pathogens | Dr Jayaseelan Murugaiyan | Sponsoring Agency SRM University - AP |
2025- | 1 | On Going |
| Acinetobacter baumannii biofilm disruption at different biofilm lifecycle stages using a molecular disruptor and its mechanism of action | Dr Jayaseelan Murugaiyan | Sponsoring Agency SRM University - AP |
2024- | 1 | On Going |
| “Comprehensive antimicrobial resistance (AMR) profiling of ESKAPE pathogen Acinetobacter baumannii isolated from environment, veterinary, and humans in Mangalagiri mandal, Andhra Pradesh” | Dr Jayaseelan Murugaiyan | Govt SERB |
2023-26 | 3 | On Going |
| Finishing studies on the mechanism underlying the lack of expression of human rotaviral nonstructural protein NSP3 in E. coli | Dr C Durga Rao | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Architecture of Rotavirus | Dr C Durga Rao | Sponsoring Agency SRM University - AP |
2024- | On Going | |
| Understanding the molecular basis for the extreme differential level of expression of genes from human and animal rotaviruses in gene-transfected cells: Implications for improving the growth of human vaccine strains | Dr C Durga Rao | Govt DBT |
2021- | Completed | |
| Unravelling meclizine’s antileishmanial potential: A repurposing approach | Dr Writoban Basu Ball | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Mechanistic Insights Meclizine’s Antileishmanial Odyssey | Dr Writoban Basu Ball | Sponsoring Agency SRM University - AP |
2024- | On Going | |
| Uncovering the role of SWEET transporters towards the development of enhanced total soluble sugar variety in tomato fruit | Dr Prateek Gupta | Sponsoring Agency SRM University - AP |
2023- | On Going | |
| Interaction of Polystyrene Micro & Nanoplastics with Tear constituents and their Impact of on Ocular Microbiome | Prof. Anil K Suresh | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Bio Engineered Nano Particles for Supported Catalysts | Prof. Anil K Suresh | Sponsoring Agency SRM University - AP |
2023- | On Going | |
| Leishmania drug targeting | Dr Writoban Basu Ball | Sponsoring Agency SRM University - AP |
2023- | On Going | |
| Characterization of a putative sialidase in Acinetobacter baumannii | Dr Sudeshna Saha | Sponsoring Agency SRM University - AP |
2024- | On Going | |
| Studies on the mechanism of ADP-ribosylation (ADPr) signalling pathway and its dysregulation in numerous human diseases: Role of ayurvedic medicine | Dr Pulak Kar | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Elucidation of spinal motoneuronal responses to decreased neuromuscular activity | Dr Pitchaiah Cherukuri | Sponsoring Agency SRM University - AP |
2024- | On Going | |
| Design of RNA-structure-guided antisense oligonucleotide for rescuing UNC13A mis-splicing in amyotrophic lateral sclerosis (ALS) | Dr Kaushik Saha | Sponsoring Agency SRM University - AP |
2024- | On Going | |
| Wound Microenvironment-Modifying Hybrid Nanocomposites of Polymer/Enzyme/ Nanozyme to accelerate Infected Diabetic Wound Healing | Dr Chiranjeevi Korupalli | Sponsoring Agency SRM University - AP |
2025- | On Going | |
| Pilot-scale ultra-efficient fixative sewage dye-degradation by “3D mega catalyst” generated using intact eggshell-waste | Prof. Anil K Suresh | Govt DBT |
2022-24 | Completed | |
| CRISPR-Cas Enhanced Phages for Precision Pathogen Eradication and Plasmid Control | Dr Sutharsan Govindarajan | Govt DST-INSPIRE |
2024- | 3 | On Going |
| Building a Collaborative Network to Conduct a Comparative Study on Antimicrobial Use and Resistance in Apparently Healthy Populations Across Multiple Regions in India | Dr Jayaseelan Murugaiyan | Industry Agency The Academy of Medical Sciences, UK |
2024-2025 | 1 | On Going |
| Novel circulating protein fingerprints for therapeutic monitoring of lymphoedema reversal following the integrative treatment | Dr Jayaseelan Murugaiyan | Industry Agency Institute of Applied Dermatology (IAD), Karasargod, Kerala |
2024- | 3.5 | On Going |
| Targeting Kennedy pathway of cellular phosphatidylethanolamine biosynthesis as a common therapeutic strategy against protozoan parasites like Leishmania donovani, Trypanosoma brucei and Entamoeba histolytica | Dr Writoban Basu Ball | Sponsoring Agency DST-SERB SRG |
2021-2023 | 2 | Completed |
| Mechanistic understanding of bacterial cytoskeleton inhibition by antibiotics and novel bacteriophage proteins | Dr Sutharsan Govindarajan | Govt SERB |
2021-24 | 3 | Completed |
| Jumbo-phage as a model for ancient cell organization | Dr Sutharsan Govindarajan | Govt DBT-Wellcome Trust |
2020-25 | 5 | On Going |
| Designing of RNA structure-guided antisense oligonucleotides to rescue SMN2 splicing for developing an indigenous therapy against spinal muscular atrophy | Dr Kaushik Saha, Dr Pitchaiah Cherukuri | Industry Agency ICMR |
2025-28 | 3 | On Going |